Top seed Rafa Nadal, who has won the tournament 10 times, also reached the last eight after dispatching compatriot Guillermo Garcia-Lopez 6-1, 6-3 and claiming a record-extending 40th consecutive set on clay.
Rafael Nadal will have his work cut out when play begins next week, not on the Caja Magica's three red dust courts, but on gaming consoles.
Defending champion and world number one Novak Djokovic won his third-straight Australian Open crown, his ninth in total.
Roger Federer kept up his hopes of finishing the year as World No 1 when he downed Frenchman Jeremy Chardy 7-6(5), 6-7(5), 6-4 in the second round of the Paris Masters on Wednesday.
Rafael Nadal is generally a slow starter but should not have any problem getting past his first-round opponent, Germany's Yannick Hanfmann.
Defending champion Novak Djokovic survived a scare.
Defending champion Novak Djokovic trounced stand-in David Goffin 6-1 6-2 for a clean sweep of his group at the ATP World Tour Finals on Thursday but spiced up a leisurely afternoon workout by picking a row with the umpire. The world number two, who will be joined in the last four by Milos Raonic after the Canadian beat Austrian Dominic Thiem 7-6(5) 6-3, began the week at London's O2 Arena quarrelling with a reporter and despite being relatively untroubled on court, there has been an edginess about the 12-times grand slam champion.
India caused a stir in Zagreb where veteran duo Leander Paes and Rohan Bopanna edged Mate Pavic and Franko Skugor in Saturday's doubles to keep alive the tie but Marin Cilic quickly doused Indian hopes with a 6-0, 6-1 win over Sumit Nagal.
He leads the men's seedings ahead of defending champ Roger Federer, with Bulgarian Grigor Dimitrov seeded third.
Garbine Muguruza was relieved to finally avoid tripping at the last hurdle and end her trophy drought
Djokovic had his personal best winning sequence of 30 consecutive sets ended as Cilic played almost flawlessly aggressive tennis to draw first blood in a magnificent duel.
Defending US Open champion Rafael Nadal and twice winner Novak Djokovic are one victory away from renewing their rivalry in the final with both expected to get through their semis on Friday.
Holder Serena Williams survived her toughest challenge yet at this year's French Open as she battled into the fourth round with a 6-4, 7-6(10) win over Frenchwoman Kristina Mladenovic in a rain-disrupted match on Saturday.
Organisers played a wrong national anthem for Moldova ahead of their tie against Belgium in Sydney. Denis Shapovalov won the battle of the next generation against Greek Stefanos Tsitsipas to help Canada to an emphatic 3-0 victory in the inaugural ATP Cup men's team event in Brisbane on Friday.
But Agassi, who began working with Djokovic at the French Open last month, says Djokovic is motivated to do the hard work required now, rather than later.
Since returning in January Rafael Nadal looks a man reborn. No wonder it is hard to find anyone not backing him to claim 'La Decima' in Paris.
Eleven-times champion Rafael Nadal booked his place in the semi-finals of the Barcelona Open semi-finals by beating German Jan-Lennard Struff 7-5, 7-5 in a hard-fought match on Friday.
Eighth seed Barty joins 1969, 1970 and 1973 champion Margaret Court and 1971 winner Evonne Goolagong-Cawley on the list of Australian women who have lifted the trophy here in the professional era.
Wimbledon debutant Eubanks ends Tsitsipas's challenge in fourth round.
The final of the Croatia event in the coastal resort of Zadar, the second leg of the tour which would have featured world number one Novak Djokovic and Russian Andrey Rublev, was cancelled as a result.
If Stanislas Wawrinka's hot streak extends another four days, the Swiss might be unstoppable in his quest for a second French Open title, three-time former champion Mats Wilander said.
Images from Day 6 of the French Open in Paris on Friday.
'The governing bodies, especially Grand Slams, need to allocate enough funds to support lower-ranked players, low-level tournaments, futures, challengers and I believe there is enough funds for those too.'
The Australian Open will lose one of its giant killers when South Korean Chung Hyeon meets American Tennys Sandgren in an unlikely quarter-final showdown at the Rod Laver Arena on Wednesday.
It will be the earliest meeting between the two since their first professional match in the second round of the 1998 Australian Open.
Bhambri, ranked 200th, recovered from a set down and registered what turned to be an emphatic 6-7, 6-3, 6-1 win over Pella in a match that lasted for two hours and 10 minutes.
The 16-times Grand Slam champion, who has been slightly ill lately, was kept on his toes before racing to victory to set up a meeting with seventh seed Stefanos Tsitsipas.
Nadal set to face Kyrgios clash in second round
Serena Williams has defeated her compatriot in four straight matches since a defeat in the quarter-finals of the 2013 Australian Open.
Bopanna being the highest-ranked doubles player in the country is automatic choice for the doubles rubber.
Team Europe swept the singles matches at the inaugural Laver Cup on Friday before Australian Nick Kyrgios and American Jack Sock took down top-ranked Rafael Nadal and Tomas Berdych in the doubles to salvage a point for Team World.
Frenchman Julien Benneteau caused a stir during an interview on French radio station RMC Sport on Sunday in which he said tournament referees were often kinder to Federer when it came to scheduling his matches.
'We've said every year that we're the 'happy slam'. But now we're saying we're the 'very safe and happy slam'.'
Here are eight men to watch on the Roland Garros clay.
World number one Novak Djokovic's French Open preparations were dealt with a blow as he suffered a 6-3, 4-6, 6-2 defeat by Russian Daniil Medvedev in the Monte Carlo Masters quarter-finals on Friday.
Andy Murray will need to be at his streetwise best to beat Stan Wawrinka in the French Open semi-finals on Friday, three-times former Roland Garros champion Mats Wilander told Reuters.
Swiss tennis maestro Roger Federer stepped up his bid for a record ninth Halle grasscourt title with a straight sets victory over Germany's Jan-Lennard Struff in the opening round on Wednesday.
Rafael Nadal overcame a temporary blip on his way to victory at the ATP Cup on Saturday
Osaka survives test to reach last 16